ea0002p43 | Endocrine tumours and neoplasia | SFE2001
Laban C
, Ogunkolade W
, Kirkpatrick K
, Bustin S
, Mokbel K
, Ghilichik M
, Carpenter R
, Jenkins P
Background: IGF-1 is a ubiquitous growth factor that has been shown to play an important role in breast tissue development and tumorigenesis. Previously we have shown that IGF-1 expression is lost in approximately 1/3 of breast carcinomas. It is unsure whether this indicates the existence of a subset of breast cancers that may behave differently clinically and on a molecular level. Aims: To assess and quantify the mRNA expression of (i) Cox-2 and c-myc, genes imp...